Lionsmane Organic Extract is rich in some physiologically important components, especially the hericenones and erinacines, are responsible for anti-cancer, immunomodulating, hypolipidemic, antioxidant and neuroprotective activities of this mushroom. H. erinaceus has also been reported to have anti-microbial, antihypertensive, anti-diabetic, wound healing properties among other therapeutic potentials. The reported health-promoting properties of the mushroom fruit bodies, mycelia, and bioactive pure compounds include antibiotic, anticarcinogenic, antidiabetic, antifatigue, antihypertensive, antihyperlipodemic, antisenescence, cardio-protective, hepatoprotective, nephron-protective, and neuroprotective properties and improvement of anxiety, cognitive function and depression. The described antiinflammatory, antioxidative, and immune-stimulating properties in cells, animals, and humans seem to be responsible for the multiple health-promoting properties.